|
| 产地 | 中国 |
| 品牌 | PrimeGene（普欣） |
| 货号 | 204-17 |
| 用途 | 细胞/科研/抗肿瘤药物 |
| 包装规格 | 5μg |
| 纯度 | > 97 %% |
| CAS编号 | |
| 是否进口 | 否 |
产品名称：Recombinant Human Thymus and Activation Regulated Chemokine/CCL17（rHuTARC/CCL17）
产品价格：
| 货号 | 规格 | 价格 |
| 204-17 | 5μg | 600 |
| 204-17 | 20μg | 1490 |
| 204-17 | 100μg | 5510 |
| 204-17 | 250μg | 9920 |
| 204-17 | 500μg | 12900 |
| 204-17 | 1mg | 17640 |
产品介绍：
| Accession | Q92583 |
| GeneID | 6361 |
| Source | Escherichia coli. |
| Molecular Weight | Approximately 8.1 kDa, a single non-glycosylated polypeptide chain containing 71 amino acids. |
| Quantity | 5μg/20μg/1000μg |
| AA Sequence | ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S |
| Purity | > 97 % by SDS-PAGE and HPLC analyses. |
| Biological Activity | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml. |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from a 0.2 μm filtered concentrated solution in 20mM PB, pH 7.4, 150mM NaCl. |
| Endotoxin | Less than 1 EU/μg of rHuTARC/CCL17 as determined by LAL method. |
| Reconstitution | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| Stability & Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied. - 1 month, 2 to 8 °C under sterile conditions after reconstitution. - 3 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Usage | This material is offered by Shanghai PrimeGene Bio-Tech for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE. |
| Reference | 1. Loftus BJ, Kim UJ, Sneddon VP, et al. 1999. Genomics, 60: 295-308. 2. Imai T, Yoshida T, Baba M, et al. 1996. J Biol Chem, 271: 21514-21. 3. Jakubzick C, Wen H, Matsukawa A, et al. 2004. Am J Pathol, 165: 1211-21. 4. Shimada Y, Takehara K, Sato S. 2004. J Dermatol Sci, 34: 201-8. 5. Sumiyoshi K, Nakao A, Setoguchi Y, et al. 2003. J Dermatol Sci, 31: 53-8. |
| Background | Human CCL17 also known as thymus and activation-related chemokine (TARC) is encoded by the CCL17 gene located on the chromosome 16 in humans. It is expressed by thymus cells constitutively and phytohemagglutinin-stimulated peripheral blood mononuclear cells transiently. CCL17 signals through the chemokine receptors CCR4 and CCR8 and displays chemotactic activity for T lymphocytes and some other leukocytes. It plays an important role in skin diseases such as atopic dermatitis, bullous pemphigoid and mycosis fungoides. CCL17 has approximately 24 – 29 % amino acid sequence identity with RANTES, MIP-1α, MIP-1β, MCP-1, MCP-2, MCP-3 and I-309. |
★高纯度、高蛋白活性
★低内毒素
★不同批次 产品稳定
★国内现货、高效快速
★Bio-Techne旗下品牌，品质保障
★无缝替代进口蛋白，质优价廉。
